Bactericidal activity of catechin-copper (II) complexes on Escherichia coli ATCC11775 in the absence of hydrogen peroxide |
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| Authors: | T Kimura N Hoshino A Yamaji F Hayakawa & T Ando |
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| Institution: | Department of Chemistry and Department of Pharmacy, Shiga University of Medical Science, and Department of Life Style Studies, School of Human Cultures, The University of Shiga Prefecture, Shiga, Japan |
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| Abstract: | Washed Escherichia coli ATCC11775 cells were killed by (–)-epigallocatechin (EGC) in the presence of a non- lethal concentration of Cu2+ (1 μmol l?1) without additional H2O2, but not by (–)-epicatechin (EC). EGC alone (< 0·1 mmol l?1) did not reduce the viability of the cells. The survival curve obtained in the presence of EGC and Cu2+ was similar to that obtained in the presence of (–)-adrenaline (EN) and Cu2+. |
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