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Adenosine kinase-deficient mutant of Saccharomyces cerevisiae
Authors:A. Iwashima  M. Ogata  K. Nosaka  H. Nishimura  T. Hasegawa
Affiliation:Department of Biochemistry, Kyoto Prefectoral University of Medicine, Kamigyo-ku, Kyoto 602, Japan; Radioisotope Laboratory, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602, Japan
Abstract:
Abstract A cordycepin-resistant mutant strain of Saccharomyces cerevisiae (CD-R2) was found to be deficient in adenosine kinase. This mutant accumulated S-adenosylhomocysteine during growth in the presence of exogenous adenosine and it grew in a pseudohyphal manner in the presence of this nucleotide.
Keywords:Cordycepin    3'-Deoxyadenosine    Saccharomyces cerevisiae    Adenosine kinase
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