In vivo tibiofemoral cartilage deformation during the stance phase of gait |
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| Authors: | Fang Liu Michal Kozanek Ali Hosseini Samuel K Van de Velde Thomas J Gill Harry E Rubash Guoan Li |
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| Institution: | 1. Bioengineering Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRJ 1215, Boston, MA 02114, USA;2. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA;1. Department of Mechanical Engineering, Stanford University, Stanford, CA, USA;2. Palo Alto VA, Bone and Joint Center, Palo Alto, CA,USA;3. Department of Orthopedic Surgery, Stanford University, Stanford, CA, USA;1. School of Rehabilitation Sciences, McMaster University, Hamilton, Canada;2. Department of Kinesiology, University of Waterloo, Waterloo, Canada;3. Qmetrics Technologies, Rochester, NY, USA;4. Escuela de Medicina, Tecnológico de Monterrey, Monterrey, NL, México;5. Department of Medicine, McMaster University, Hamilton , Canada;1. School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada;2. School of Physical & Occupational Therapy, McGill University, Montreal, Quebec, Canada;3. Wolf Orthopaedic Biomechanics Laboratory and School of Physical Therapy, University of Western Ontario, London, Ontario, Canada;4. Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada;1. Orthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Newton, MA, USA;2. Department of Orthopedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA;3. Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA;4. Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China;2. Department of Mechanical Engineering, University of Delaware, Newark, DE, USA;3. Department of Biomedical Engineering, University of Delaware, Newark, DE, USA;1. Department of Orthopaedic Surgery, Duke University, Durham, NC, USA;2. Department of Biomedical Engineering, Duke University, Durham, NC, USA;3. Department of Radiology, Duke University, Durham, NC, USA;4. Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA |
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| Abstract: | The knowledge of articular cartilage contact biomechanics in the knee joint is important for understanding the joint function and cartilage pathology. However, the in vivo tibiofemoral articular cartilage contact biomechanics during gait remains unknown. The objective of this study was to determine the in vivo tibiofemoral cartilage contact biomechanics during the stance phase of treadmill gait. Eight healthy knees were magnetic resonance (MR) scanned and imaged with a dual fluoroscopic system during gait on a treadmill. The tibia, femur and associated cartilage were constructed from the MR images and combined with the dual fluoroscopic images to determine in vivo cartilage contact deformation during the stance phase of gait. Throughout the stance phase of gait, the magnitude of peak compartmental contact deformation ranged between 7% and 23% of the resting cartilage thickness and occurred at regions with thicker cartilage. Its excursions in the anteroposterior direction were greater in the medial tibiofemoral compartment as compared to those in the lateral compartment. The contact areas throughout the stance phase were greater in the medial compartment than in the lateral compartment. The information on in vivo tibiofemoral cartilage contact biomechanics during gait could be used to provide physiological boundaries for in vitro testing of cartilage. Also, the data on location and magnitude of deformation among non-diseased knees during gait could identify where loading and later injury might occur in diseased knees. |
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