Effects of K+, Ba2+ and Ca2+ on the excitable membrane in Paramecium tetraurelia |
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| Affiliation: | 1. Department of Biotechnology Engineering, School of Chemical Engineering, University of Tehran, Tehran, Iran;2. Department of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran;3. Department of Chemical Engineering, Faculty of Engineering, University of Tehran, Tehran, Iran;1. Centre for Pharmacoepidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden;2. Central Health Directorate, Friuli Venezia Giulia region, Riva Nazario Sauro 8, Trieste 34100, Italy |
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| Abstract: | ![]()
- 1.1. The effects of Ba2+ and K+ ions on the membrane currents of Paramecium tetraurelia under a voltage clamp were investigated.
- 2.2. External Ba2+ suppresses the inward-going K-current and the Ca-induced K-outward current and changes the activation and inactivation kinetics of transient inward current through the Ca-channel.
- 3.3. K+ increases the Ca-induced K-conductances but little affects the leakage conductance.
- 4.4. The resting potentials by changing those ionic concentrations shift the voltage sensitivities of all voltage sensitive channels, simultaneously.
- 5.5. The competition between ions to the channel responses was discussed.
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