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Effective extracellular vesicles in glioma: Focusing on effective ncRNA exosomes and immunotherapy methods for treatment |
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| Authors: | Sulieman Ibraheem Shelash Al-Hawary Sharif Alhajlah Bokov Dmitry Olegovich Ahmed Hjazi Pranchal Rajput Saad Hayif Jasim Ali Munther Abosoda Ali Ihsan Shamam Kareem Oudah Yasser Fakri Mustafa |
| Affiliation: | 1. Department of Business Administration, Business School, Al al-Bayt University, Al-Mafraq, Jordan;2. Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Shaqraa, Saudi Arabia;3. Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation;4. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia;5. School of Applied and Life Sciences, Uttaranchal University, Dehradun, India;6. Department of Medical Laboratory, College of Health and Medical Technology, Al-Ayen University, Thi-Qar, Iraq;7. College of Pharmacy, The Islamic University, Najaf, Iraq College of Pharmacy, The Islamic University of Al Diwaniyah, Al Diwaniyah, Iraq College of Pharmacy, The Islamic University of Babylon, Babylon, Iraq;8. Department of Medical Laboratories Techniques, Imam Ja'afar Al-Sadiq University, Iraq;9. College of Pharmacy, National University of Science and Technology, Dhi Qar, Iraq;10. Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul, Iraq |
| Abstract: | This comprehensive article explores the complex field of glioma treatment, with a focus on the important roles of non-coding RNAsRNAs (ncRNAs) and exosomes, as well as the potential synergies of immunotherapy. The investigation begins by examining the various functions of ncRNAs and their involvement in glioma pathogenesis, progression, and as potential diagnostic biomarkers. Special attention is given to exosomes as carriers of ncRNAs and their intricate dynamics within the tumor microenvironment. The exploration extends to immunotherapy methods, analyzing their mechanisms and clinical implications in the treatment of glioma. By synthesizing these components, the article aims to provide a comprehensive understanding of how ncRNAs, exosomes, and immunotherapy interact, offering valuable insights into the evolving landscape of glioma research and therapeutic strategies. |
| Keywords: | glioma immunotherapy miRNA exosomes |