| Investigation of various structures of DNA molecules (Ⅲ)——Coil-globe transition of λ-DNA induced by cationic surfactant |
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| 作者姓名： | 冯喜增 林璋 王琛 白春礼 |
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| 作者单位： | Institute of Chemistry，Chinese Academy of Sciences，Beijing 100080，China |
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| 基金项目： | Project supported by the Ninth Five-Year Great，Important Project of the Chinese Academy of Sciences，National Postdoctoral Science Foundation of China. |
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| 摘 要： | The structure transition of λ-DNA induced by cationic surfactant cellar media was investigated by using CD, SEM and AFM. The experimental data of CD revealed that λ-DNA can be induced from B-form to a collapsed structure with the addition of the cationic surfactant CTAB to the system. The condensed process of λ-DNA from coil state to small globular state (diameter about 1.25 μm) and finally big globular state (diameter about 5.4 μm) was observed by using SEM and AFM.
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