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| Liver development in zebrafish （Danio rerio） | |
| 引用本文： | Ting Tao Jinrong Peng. Liver development in zebrafish （Danio rerio）[J]. 遗传学报, 2009, 36(6): 325-334. DOI: 10.1016/S1673-8527(08)60121-6 |
| 作者姓名： | Ting Tao Jinrong Peng |
| 作者单位： | College of Animal Science, Zhejiang University, Hangzhou 310029, China |
| 摘 要： | Liver is one of the largest internal organs in the body and its importance for metabolism, detoxification and homeostasis has been well established. In this review, we summarized recent progresses in studying liver initiation and development during embryogenesis using zebrafish as a model system. We mainly focused on topics related to the specification of hepatoblasts from endoderm, the formation and growth of liver bud, the differentiation of hepatocytes and bile duct cells from hepatoblasts, and finally the role of mesodermal signals in controlling liver development in zebrafish. |
| 关 键 词： | 肝脏 斑马鱼 内胚层 肝细胞 |
| 收稿时间： | 2009-02-16 |
Liver development in zebrafish (Danio rerio) |
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| Ting Tao,Jinrong Peng. Liver development in zebrafish (Danio rerio)[J]. Journal of Genetics and Genomics, 2009, 36(6): 325-334. DOI: 10.1016/S1673-8527(08)60121-6 | |
| Authors: | Ting Tao Jinrong Peng |
| Affiliation: | College of Animal Science, Zhejiang University, Hangzhou 310029, China |
| Abstract: | Liver is one of the largest internal organs in the body and its importance for metabolism, detoxification and homeostasis has been well established. In this review, we summarized recent progresses in studying liver initiation and development during embryogenesis using zebrafish as a model system. We mainly focused on topics related to the specification of hepatoblasts from endoderm, the formation and growth of liver bud, the differentiation of hepatocytes and bile duct cells from hepatoblasts, and finally the role of mesodermal signals in controlling liver development in zebrafish. |
| Keywords: | zebrafish model organism liver development endoderm |
| 本文献已被 维普 万方数据 ScienceDirect 等数据库收录！ | |