Regulation of bacterial physiological processes by three types of protein phosphorylating systems |
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Authors: | M H Saier L F Wu J Reizer |
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Institution: | Department of Biology, University of California, San Diego, La Jolla 92093. |
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Abstract: | A single type of protein-phosphorylating system, the ATP-dependent protein kinases, is employed in the regulation of a variety of cellular physiological processes in eukaryotes. By contrast, recent work with bacteria has revealed that three types of protein-phosphorylating systems are involved in regulation: (1) the classical protein kinases, (2) the newly discovered sensor-kinase/response-regulator systems, and (3) the multifaceted phosphoenolpyruvate-dependent phosphotransferase system. Physiological and mechanistic aspects of these three evolutionarily distinct systems are discussed. |
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