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Identification and quantification of DNA repair protein poly(ADP ribose) polymerase 1 (PARP1) in human tissues and cultured cells by liquid chromatography/isotope-dilution tandem mass spectrometry
Institution:1. Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, United States;2. Department of Molecular Medicine, Institute of Health Sciences, Dokuz Eylul University, Izmir, Turkey;3. Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States;4. Department of Toxicology, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara, Turkey;1. Department of General, Visceral and Thoracic Surgery, University Medical Center of Hamburg-Eppendorf, Germany;2. Department of Medicine I, University Medical Center of Hamburg-Eppendorf, Germany;1. Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, United States;2. Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, United States;3. Center for Drug Discovery, Northeastern University, Boston, MA, 02115, United States;4. Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, United States;5. Pharmaceutical Sciences Department, Northeastern University, Boston, MA, 02115, United States;1. Oregon Institute of Occupational Health Sciences, Oregon Health & Science University Portland, OR 97239-3098, United States;2. Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg MD 20899-8311, United States;3. Department of Molecular and Medical Genetics, Oregon Health & Science University Portland, OR 97239-3098, United States;4. Department of Physiology and Pharmacology, Oregon Health & Science University Portland, OR 97239-3098, United States;1. Vocational School of Health Services, Izmir University of Economics, Izmir, Turkey;2. Department of Neuroscience, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey;3. Department of Molecular Medicine, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey;4. Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Bethesda, MD, 20892, USA;5. Department of Psychiatry, School of Medicine, Dokuz Eylul University, Izmir, Turkey;6. Department of Psychiatry, Mardin State Hospital, Mardin, Turkey;7. Department of Psychology, Istanbul Gelişim University, Istanbul, Turkey, Turkey;8. Department of Medical Biochemistry, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey;9. Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA;1. Department of Pharmacological Sciences, Stony Brook University, Renaissance School of Medicine, Basic Science Tower 8-140, Stony Brook, New York, 11794, USA;2. Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, NC, 27709-2233, USA;3. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA
Abstract:
Keywords:PARP1  DNA damage  DNA repair proteins  Cancer biomarkers  Isotope-dilution mass spectrometry  Overexpression
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