Localization of ribosomal RNA genes on human acrocentric chromosomes |
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| Authors: | S Spadari R Di Lernia G Simoni G Pedrali-Noy and L De Carli |
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| Institution: | (1) Laboratorio di Genetica Biochimica ed Evoluzionistica, C.N.R., Pavia, Italy;(2) Istituto di Genetica, Università di Pavia, Pavia, Italy;(3) Istituto di Biologia Generale Faculty of Medicine, University of Milan, Milan, Italy |
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| Abstract: | Summary Clonal derivatives of a human heteroploid cell line, with different numbers of acrocentric chromosomes, show different rDNA contents. A linear relationship has been found between the rDNA content and the relative mass of the acrocentric chromosomes (D+G) expressed as the ratio between the mass of their DNA and the mass of the DNA of the whole chromosomal complement. The results suggest that human rRNA genes are located exclusively on the chromosomes of the groups D and G and that all these chromosomes contain rRNA genes. |
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