Production of neutralizing antibody to rabies and vesicular stomatitis viruses by hybrid cell lines |
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| Authors: | K K Sethi H Brandis |
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| Institution: | Institut für Med. Mikrobiologie und Immunologie, Universität Bonn, 5300 Bonn, Venusberg, West Germany |
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| Abstract: | Hybrid cell lines were obtained following fusion of P 3 × 63 Ag-8 myeloma cells with spleen cells derived from BALB/c mice immunized either with rabies virus or with vesicular stomatitis virus. Hybrid cell lines were selected which continued to secrete rabies virus or vesicular stomatitis virus neutralizing antibody specifically directed against coat glycoprotein of respective viruses. |
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