Divalent cation and lipid-protein interactions of biomembranes |
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| Authors: | F Y Yang Y G Huang Y P Tu |
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| Institution: | (1) National Laboratory of Biomacromolecules,Institute of Biophysics, Academia Sinica, 100101 Beijing, China |
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| Abstract: | Divalent cations play an important role in the functions of biomembranes. This review deals with three topics: (1) Mg2+-mediated change in physical state of phospholipid induces conformation and activity change of reconstituted mitochondrial H+-ATPase, (2) a proper transmembrane Ca2+ gradient is essential for the higher enzymatic activity of adenylate cyclase, and (3) role of transmembrane Ca2+ gradient in the modulation of reconstituted sarcoplasmic reticulm Ca2+-ATPase activity. |
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| Keywords: | divalent cation lipid-protein interaction H+-ATPase adenylate cyclase Sarcoplasmic reticulum Ca2+-ATPase |
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