| circRNAs在成骨细胞分化中的调控作用 |
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| 引用本文： | 王欣,王兴.circRNAs在成骨细胞分化中的调控作用[J].中国细胞生物学学报,2020(2):336-341. |
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| 作者姓名： | 王欣 王兴 |
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| 作者单位： | 山西医科大学口腔医学院·口腔医院 |
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| 基金项目： | 国家自然科学基金(批准号:81801004)资助的课题。 |
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| 摘 要： | 环状RNAs(circular RNAs,circRNAs)是一类新型内源性非编码RNAs,在调节生长发育、疾病发展等方面具有重要的生物学功能。新近研究证实,circRNAs参与调控牙周膜干细胞和骨髓干细胞等的成骨细胞分化。该文就当前circRNAs在成骨细胞分化中的最新研究进展作一综述,以帮助开发骨科疾病新疗法。
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| 关 键 词： | 环状RNA 牙周膜干细胞 骨髓干细胞 成骨细胞分化 |
Regulation of circRNAs in Osteogenic Differentiation |
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| Authors: | WANG Xin WANG Xing |
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| Institution: | (Shanxi Medical University School and Hospital of Stomatology,Taiyuan 030001,China) |
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| Abstract: | circRNAs(circular RNAs),a novel class of endogenous noncoding RNAs,play a key role in regulating growth and development of diseases.Recent studies confirmed that circRNAs were involved in regulating osteogenic differentiation of PDLSCs(periodontal ligament stem cells)and BMSCs(bone marrow stem cells).This review focuses on the latest research progress of circRNAs in osteogenic differentiation,to help develop new therapies for bone diseases. |
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| Keywords: | circRNAs PDLSCs BMSCs osteogenic differentiation |
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