|
|||||
|
|
Regional localisations and linkage relationships of seven RFLPs and myotonic dystrophy on chromosome 19 |
|
| Authors: | D J Shaw A L Meredith M Sarfarazi H G Harley S M Huson J D Brook L Bufton M Litt T Mohandas P S Harper |
| Institution: | (1) Section of Medical Genetics, University of Wales College of Medicine, Heath Park, CF44XN Cardiff, UK;(2) Department of Biochemistry, Oregon Health Sciences University, 97201 Portland, OR, USA;(3) Department of Medical Genetics, Oregon Health Sciences University, 97201 Portland, OR, USA;(4) Harbor UCLA Medical Center, 1000 West Carson Street, 90509 Torrance, CA, USA |
| Abstract: | Summary We have studied the genetic linkage relationships of seven DNA polymorphisms on chromosome 19, with each other and with the myotonic dystrophy locus. The DNA sequences were localised to various regions of the chromosome using translocations in somatic cell hybrids. These results provide the basis for a linkage map of most of chromosome 19, and suggest that the myotonic dystrophy locus is close to the centromere. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |