乙型病毒性肝炎与上消化道血管粘膜损伤性疾病的临床分析

目的:研究乙型病毒性肝炎与上消化道血管粘膜损伤性疾病相关性。方法:回顾性分析经纤维胃镜检查的121例患者的临床资料,全部病例行纤维胃镜检查,同时采用酶免法检测病人血清HBV.121例患者分为观察组83例与对照组38例。结果:观察组的83例胃病患者即消化性溃疡,出血性或糜烂性胃十二指肠炎。患者的HBV总阳性率为65.1%。对照组38例即非血管粘膜损伤组的单纯性浅表性胃十二指肠炎患者,其HBV总阳性率为42.2%。观察组明显高于对照组,二组阳性率在统计学上有显著性差异(P<0.05)。结论:提示上消化道血管粘膜损伤与HBV感染密切相关。如何有效保护消化道血管粘膜的完整性是降低HBV感染率的重要因素。

Analysis of Correlation between Viral Hepatitis B and Injury Disease of Blood Vessel and Mucous Membrane of Upper Gastrointestinal Tract

Objective: To investigate the correlation between viral hepatitis B and the injury disease of blood vessel and mucous membrane(IDBVMM) of upper gastrointestinal tract(UGIT). Methods: 121 patients were divided into observation group (n=83) and control group(n=38). All the patients in the two groups were detected by fibergastroscope,and HBV level in their sera was determined by ELISA. The clinical data of the patients were retrospectively analysed. Results: In observation group,the 83 patients, whose total positive rate(TPR) of HBV was 65.1%, suffered from peptic ulcer(PU), hemorrhagic or erosive gastroduodenitis; while in control group,the patients, whose TPR of HBV was 42.2%, suffered from simple and superficial gastritis. There was significant difference in TPR of HBV between the two groups(P<0.05). Conclusion: This study showed that IDBVMM of UGIT was related to infection of HBV. Therefore, how to keep the blood vessel and mucous membrane of UGIT intact would be the important factor of reducing the infection rate of HBV.