The genetics of position-effect variegation modifying loci in Drosophila melanogaster |
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| Authors: | G. Wustmann J. Szidonya H. Taubert G. Reuter |
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| Affiliation: | (1) Department of Genetics, Section Biosciences, Martin Luther University Halle, Domplatz 1, DDR-4020 Halle/S.;(2) Institute of Genetics, Biological Research Center, Hungarian Academy of Sciences, POB 521, H-6701 Szeged, Hungary |
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| Abstract: | Summary The dose dependent effects of position-effect variegation (PEV) modifying genes were studied in chromosome arms2L, 2R and3R. Four groups of PEV modifying genes can be distinguished: haplo-abnormal suppressor and enhancer loci with or without a triplo-effect. using duplications four triplo-abnormal suppressor and four triplo-abnormal enhancer functions were localized. In two cases we proved that these functions correspond to a converse haplo-abnormal one. Altogether 43 modifier loci were identified. Most of these loci proved not to display significant triplo-effects (35). The group of haplo-abnormal loci with a triplo-effect may represent genes which play an important role in heterochromatin packaging. |
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| Keywords: | Drosophila melanogaster Position-effect variegation Modifier loci Gene dosage effects |
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