1. Department of Microbiology, Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Republic of Singapore;2. Heart Research Institute and Centenary Institute Newtown, Sydney, NSW 2042, Australia;3. School of Medical and Molecular Biosciences, Faculty of Science, University of Technology, Sydney, NSW 2007, Australia;4. Singapore Immunology Network, BMSI, A-STAR, Singapore 138648, Republic of Singapore;5. Department of Molecular and Cellular Physiology, LSU Health Sciences Center, Shreveport, LA 71130, USA