1. Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672;2. Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672;3. Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore 138672;4. NUS Graduate School for Integrative Sciences and Engineering, Singapore 117456;5. Department of Biochemistry, National University of Singapore, Singapore 117597;6. Department of Biological Sciences, National University of Singapore, Singapore 117543;7. School of Biological Sciences, Nanyang Technological University, Singapore 637551
Abstract:
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Highlights? Modified small-scale ChIP-seq method applicable to small number of cells ? Genome-wide maps of H3K4me3, H3K27me3, H3K27ac, and H2BK20ac of germ cells in vivo ? Identification of active and inactive regulatory elements in germ cells in vivo ? Germ cell H3K27me3 regions are enriched for retrotransposon repeats
