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A QTL with major effect on milk yield and composition maps to bovine Chromosome 14
Authors:Wouter Coppieters  Juliette Riquet  Juan-José Arranz  Paulette Berzi  Nadine Cambisano  Bernard Grisart  Latifa Karim  Fabienne Marcq  Laurence Moreau  Carine Nezer  Patricia Simon  Pascal Vanmanshoven  Danny Wagenaar  Michel Georges
Institution:(1) Department of Genetics, Faculty of Veterinary Medicine, University of Liège (B43), 20 Bd de Colonster, 4000-Liège, Belgium, BE
Abstract:A whole genome scan was undertaken in a granddaughter design comprising 1158 progeny-tested bulls in order to map QTL influencing milk yield and composition. In this paper we report the identification of a locus on the centromeric end of bovine Chromosome (Chr) 14, with major effect on fat and protein percentage as well as milk yield. The genuine nature of this QTL was verified using the grand2-daughter design, that is, by tracing the segregating QTL alleles from heterozygous grandsires to their maternal grandsons and confirming the predicted QTL allele substitution effect. Received: 30 December 1997 / Accepted: 21 February 1998
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