An endonuclease activity in Bacillus subtilis specific for UV-irradiated DNA |
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| Authors: | Eiji Hayase Takehiko Shibata Tadahiko Ando |
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| Affiliation: | Microbiology Laboratory, The Institute of Physical and Chemical Research, Wako-shi Saitama, 351. Japan |
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| Abstract: | An enzyme activity specific for UV-DNA1 was found in the extract of (Marburg 168). The enzyme preparation obtained from the extract by ammonium sulfate precipitation acts on UV-DNA endonucleolytically and induces single strand breaks. The number of single strand breaks introduced in DNA is proportional to UV dose. |
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