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Cycloartanes from the Gum Resin of Gardenia gummifera L.f.
Authors:Wolfgang Schuehly  Kalpana Amancha  Ravi Kiran Reddy Nallamaddi  Anupama Palepu  Yogita Thakur  Venkat Rao Adavi Rao Belvotagi  Ravi Kumar Bobbala  Venkata Narasimha Appa Rao Achanta  Olaf Kunert
Institution:1. Institute of Pharmaceutical Sciences, Karl‐Franzens‐University Graz, Heinrichstrasse 28, AT‐8010 Graz (phone: +43‐681‐20177980);2. Institute of Zoology, Karl‐Franzens‐University Graz, Universit?tsplatz 2, AT‐8010 Graz;3. University College of Pharmaceutical Sciences, Kakatiya University, Warangal?–?506009, Andhra Pradesh, India
Abstract:The gum resin exuding from the leaf buds of Gardenia gummifera was investigated. Eight new cycloartane triterpenes, 1 – 6, 8 , and 10 , together with two known triterpenes, 25‐hydroxycycloart‐23‐en‐3‐one ( 7 ) and cycloartenone ( 9 ), were isolated and identified by extensive NMR spectroscopy. For cycloartenone ( 9 ), full NMR assignments are given as these data were not available in the literature. Eight compounds possess a C(3)?O group, two are 3,4‐secocycloartanes bearing a free C(3)OOH group; in one of the cycloartanes, gummiferartane‐9 ( 10 ), ring A occurs as a seven‐membered lactone.
Keywords:Gardenia gummifera  Cycloartanes  Gum resin
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