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The Genus Pluchea: Phytochemistry,Traditional Uses,and Biological Activities
Authors:Hidayat Hussain  Ahmed Al‐Harrasi  Ghulam Abbas  Najeeb Ur Rehman  Fazal Mabood  Ishtiaq Ahmed  Muhammad Saleem  Teunis van Ree  Ivan R. Green  Saeed Anwar  Amin Badshah  Afzal Shah  Iftikhar Ali
Affiliation:1. UoN Chair of Oman's Medicinal Plants and Marine Products, University of Nizwa, Birkat Al‐Mauz, Nizwa 616, Sultanate of Oman (phone: +968‐92828487;2. fax: +968‐25446289);3. Department of Chemistry, CIIT, Abbottabad Campus, Abbottabad‐22060, Pakistan;4. Karlsruhe Institute of Technology (KIT), DFG Centre for Functional Nanostructures, Wolfgang Gaede Strasse 1, D‐76131 Karlsruhe;5. Department of Chemistry, The Islamia University of Bahawalpur, Baghdad Campus‐ul‐Jadid, Bahawalpur, Pakistan;6. Department of Chemistry, University of Venda, Private Bag X5050, Thohoyandou 0950 South Africa;7. Department of Chemistry, University of Stellenbosch, Stellenbosch 7600, South Africa;8. Department of Botany, Abdul Wali Khan University, Mardan, Pakistan;9. Department of Chemistry, Quaid‐i‐Azam University, 45320 Islamabad, Pakistan;10. Department of Chemistry, Karakoram International University, 15100 Gilgit‐Baltistan, Pakistan
Abstract:
In this review, literature data on phytochemical and biological investigations on the genus Pluchea are compiled. Pluchea is a genus of flowering plants in the Asteraceae family and comprises ca. 80 species distributed mainly in Northern and Southern America, Africa, Asia, and Australia. Sesquiterpenoids and flavonoids are the main constituents of this genus. Compounds isolated from plants of the Pluchea genus display a variety of biological properties, viz., anticancer, antileishmanial, immunosuppressive, antioxidant, anti‐acetylcholinesterase, antimicrobial, trypanocidal, hepatoprotective, cytotoxic, larvicidal, anti‐ulcer, anti‐inflammatory, and antinociceptive activities.
Keywords:Pluchea species  Sesquiterpenoids  Flavonoids  Biological activity
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