Unusual Secondary Metabolites from Astragalus halicacabus Lam. |
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| Authors: | Basile‐Jimmy Djimtombaye Özgen Alanku?‐Çal??kan Derya Gülcemal Ikhlas A Khan Hüseyin An?l Erdal Bedir |
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| Institution: | 1. Ege University, Faculty of Science, Department of Chemistry, Bornova, 35100, ?zmir, Turkey;2. Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, USA;3. Ege University, Faculty of Engineering, Department of Bioengineering, Bornova, 35100 ?zmir, Turkey, (phone: +90‐2323884955;4. fax: +90‐2323884955) |
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| Abstract: | From the whole plant of Astragalus halicacabus (Sect. Halicacabus), a new cycloartane‐type glycoside, (20R,24S)‐3‐O‐α‐L ‐arabinopyranosyl‐(1→2)‐β‐D ‐xylopyranosyl]‐20,24‐epoxy‐16‐O‐β‐D ‐glucopyranosyl‐3β,6α,16β,25‐tetrahydroxycycloartane, and a new glycoside, 3‐O‐β‐D ‐apiofuranosyl‐(1→2)‐β‐D ‐glucopyranosyl]maltol were isolated together with seven known cycloartane‐type glycosides, i.e., cyclocanthoside D, askendosides D, F, and G, cyclosieversioside G, cyclostipuloside A, elongatoside, and a known maltol glucoside, 3‐O‐β‐D ‐glucopyranosylmaltol. The structures were elucidated by means of high‐resolution mass spectrometry, and extensive 1D‐ and 2D‐NMR spectroscopic analysis. This is the first phytochemical work on A. halicacabus, and a maltol glycoside was encountered for the first time in the Leguminosae family. |
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| Keywords: | Astragalus halicacabus Cycloartanes Maltol glycosides Glycosides |
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