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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Authors:Olivia Sveidahl Johansen  Tao Ma  Jakob Bondo Hansen  Lasse Kruse Markussen  Renate Schreiber  Laia Reverte-Salisa  Hua Dong  Dan Ploug Christensen  Wenfei Sun  Thorsten Gnad  Iuliia Karavaeva  Thomas Svava Nielsen  Sander Kooijman  Cheryl Cero  Oksana Dmytriyeva  Yachen Shen  Maria Razzoli  Shannon L O’Brien  Zachary Gerhart-Hines
Institution:1. Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark;2. Embark Biotech ApS, Copenhagen, Denmark;3. Center for Adipocyte Signaling, University of Southern Denmark, Odense, Denmark;4. Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark;5. Institute of Molecular Biosciences, University of Graz, Graz, Austria;6. Institute of Pharmacology and Toxicology, University Hospital, University of Bonn, Bonn, Germany;7. Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland;8. Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands;9. Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands;10. Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, USA;11. Institute for Diabetes, Obesity, and Metabolism, Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA;12. Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK;13. Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham, UK;14. Institute of Pharmacology and Toxicology and Bio-Imaging Center, University of Würzburg, Würzburg, Germany;15. Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark;16. Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, Copenhagen, Denmark;17. MRC Laboratory of Molecular Biology, Cambridge, UK;18. Department of Structural Biology and Center for Data Driven Discovery, St. Jude Children’s Research Hospital, Memphis, TN, USA;19. Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Copenhagen, Denmark;20. Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA;21. Department of Medicine (H7), Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden;22. Centre of Inflammation and Metabolism and Centre for Physical Activity Research, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark;23. BioTechMed-Graz, Graz, Austria
Abstract:
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