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Cytotoxic activities of Hypericum perforatum L. extracts against 2D and 3D cancer cell models
Authors:Matić  Ivana Z  Ergün  Sercan  Đorđić Crnogorac  Marija  Misir  Sema  Aliyazicioğlu  Yüksel  Damjanović  Ana  Džudžević-Čančar  Hurija  Stanojković  Tatjana  Konanç  Kalbiye  Petrović  Nina
Institution:1.Institute of Oncology and Radiology of Serbia, Pasterova 14, Belgrade, Serbia
;2.Department of Medical Biology, Faculty of Medicine, Ondokuz May?s University, Samsun, Turkey
;3.Department of Biochemistry, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey
;4.Department of Medical Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey
;5.Department of Natural Sciences in Pharmacy, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
;6.Department of Laboratory and Veterinary Health, Ulubey Vocational Higher School, Ordu University, Ordu, Turkey
;7.“VIN?A” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Mike Alasa 12-14, Belgrade, Serbia
;
Abstract:Cytotechnology - Six extracts were obtained from plant species Hypericum perforatum L., collected at Samsun in Turkey. The aim of this study was to examine the mechanisms of the anticancer activity...
Keywords:Hypericum perforatum  Cytotoxic activity  Matrix-metalloproteinase  Vascular endothelial growth factor  miR128/193a-5p/335  3D HeLa spheroids
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