Alpha-methylene-gamma-lactone fused to steroidal ring D as potential antitumor agent |
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Authors: | M Kocór M M Kabat J Wicha W Peczyńska-Czoch |
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Affiliation: | Institute of Organic Chemistry of the Polish Academy of Sciences, 01-224 Warsaw, Poland;L. Hirszfeld Institute of Immunology and Experimental Therapy, 53-114 Wroc?law, Poland |
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Abstract: | Steroidal alpha-methylene-gamma-lactone la has been synthesised from 3 beta-hydroxy-5-androsten-17-one 2 and showed to be active against HeLa cells. |
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