| PTP 及其在植物MAPK 途径中的作用 |
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| 引用本文： | 赖辉煌,王宏斌,王金发.PTP 及其在植物MAPK 途径中的作用[J].植物学报,2007,24(5):677-685. |
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| 作者姓名： | 赖辉煌 王宏斌 王金发 |
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| 作者单位： | 中山大学生命科学学院, 有害生物控制与资源利用国家重点实验室, 基因工程教育部重点实验室, 广州 510275 |
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| 基金项目： | 国家自然科学基金,中山大学校科研和教改项目 |
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| 摘 要： | 蛋白酪氨酸磷酸酶(protein tyrosine phosphatases, PTPs)是一个结构多样的磷酸酶家族, 含有高度保守的催化结构域。在植物体内, PTP主要的靶蛋白是促细胞分裂剂激活性蛋白激酶(mitogen-activated protein kinase, MAPK)。MAPK级联途径参与有机体的发育、细胞增殖、激素调节以及逆境胁迫的信号转导, PTP在MAPK级联途径中主要起负调控作用。本文就PTP的结构和功能、MAPK在植物中的作用及PTP在MAPK级联途径中的功能进行综述, 并着重介绍PTP在拟南芥中的研究进展。
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| 关 键 词： | 拟南芥 促细胞分裂剂激活性蛋白激酶 磷酸化 蛋白酪氨酸磷酸酶 |
| 收稿时间： | 2006-11-07 |
| 修稿时间： | 2007-01-28 |
Study on Protein Tyrosine Phosphatases and Their Function in Mitogen-activated Protein Kinase Cascades in Plants |
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| Huihuang Lai Hongbin Wang Jinfa Wang.Study on Protein Tyrosine Phosphatases and Their Function in Mitogen-activated Protein Kinase Cascades in Plants[J].Bulletin of Botany,2007,24(5):677-685. |
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| Authors: | Huihuang Lai Hongbin Wang Jinfa Wang |
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| Institution: | The State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China |
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| Abstract: | Protein tyrosine phosphatases (PTPs) are a large and structurally diverse family, and contain a highly conserved catalysis domain. In plants, they interact with the mitogen-activated protein kinase (MAPK), which has an important role in development, cell proliferation, hormone regulation and stress signaling. PTP is a negative regulating factor in the MAPK pathway.In this paper, we review the recent advances in study of PTP and the role of MAPK in plants, including the structure of PTP and its functions in the MAPK pathway, especially in Arabidopsis thaliana. |
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| Keywords: | , |
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