| GnRH脉冲模式对FSH分泌的影响 |
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| 引用本文： | 王新,谭建华,赖小平,万忠海,韦旭斌.GnRH脉冲模式对FSH分泌的影响[J].细胞生物学杂志,2011(3). |
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| 作者姓名： | 王新 谭建华 赖小平 万忠海 韦旭斌 |
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| 作者单位： | 青岛农业大学动物科学技术学院;广州中医药大学中药学院;解放军军事医学科学院军事兽医研究所;吉林大学畜牧兽医学院; |
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| 基金项目： | 国家自然科学基金(No.30571356); 青岛农业大学课题(No.630810,No.SYJK09-05,No.XJG0906); 广州中医药大学博士后科研启动金(No.B3YH1008)资助项目~~ |
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| 摘 要： | 本文目的是进行GnRH脉冲模式对FSH分泌影响的研究。用GnRH以不同的脉冲振幅、不同的频率对GTH细胞进行刺激后,检测FSH的24 h分泌量。结果表明,FSH的24 h分泌量,以频率为120 min、振幅20 nmol/L时的GnRH脉冲模式为最高,并且随着GnRH刺激频率的增快或减慢,FSH的分泌量均呈逐渐减少趋势。所以,GnRH脉冲频率本身就是一个调控信号,不同脉冲频率GnRH对FSH表达有着明显不同的影响,在相同振幅条件下,低频脉冲刺激(120 min间隔)时FSH的分泌达到高峰。
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| 关 键 词： | FSH GnRH 脉冲 |
The Effect of GnRH Impulse Mode on FSH |
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| Xin Wang,Jian-Hua Tan,Xiao-Ping Lai,Zhong-Hai Wan,Xu-Bin Wei.The Effect of GnRH Impulse Mode on FSH[J].Chinese Journal of Cell Biology,2011(3). |
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| Authors: | Xin Wang Jian-Hua Tan Xiao-Ping Lai Zhong-Hai Wan Xu-Bin Wei |
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| Institution: | Xin Wang~(1,2),Jian-Hua Tan~3,Xiao-Ping Lai~2,Zhong-Hai Wan~(3*),Xu-Bin Wei~(4*) (1 Animal Science College of Qingdao Agricultural University,Qingdao 266109,China,2 Traditional Chinese Medical Academy of Guangzhou University of Chinese Medicine,Guangzhou 510006,3 Institute of Military Veterinary Academy of Military Medical Science,PLA,Changchun 130062,4 Pasturage and Theriatrics School,Jilin University,China) |
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| Abstract: | This article aims to research the influence of GnRH impulse mode on the secretion of FSH.The stimulation experiment of GnRH at different frequencies and with different amplitude lasted 24 h,and then the secretory volume of FSH was detected.The result shows the secretory volume of FSH reaches the top when the frequency of GnRH impulse is 120 min and the vibration amplitude of it is 20 nmol/L,moreover,with the hurrying up or the stepping down of the frequency of GnRH stimulation,the secretion of FSH is both r... |
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| Keywords: | FSH GnRH impulse |
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