高渗盐水联合沙丁胺醇雾化治疗小儿毛细支气管炎的疗效比较

目的:观察高渗盐水联合沙丁胺醇雾化吸入治疗小儿毛细支气管炎疗效。方法:选取2012年1月~2013年2月在我院接受治疗的毛细支气管炎患儿78例,随机分为治疗组和对照组,每组各39例。两组均采用综合性治疗及对症处理,在此基础上,对照组给予生理盐水联合沙丁胺醇雾化吸入,治疗组给予3.6%高渗盐水联合沙丁胺醇雾化吸入。观察两组痰液炎性细胞计数差值及临床疗效。结果:治疗组总有效率94.87%(37/39),对照组总有效率82.05%(32/39),显著差异有统计意义(P0.05)。治疗组患儿雾化吸入前和治疗5 d后痰液细胞总数、淋巴细胞数和中性淋巴细胞数均低于对照组(P0.01)。结论:联合使用3.6%的高渗盐水和雾化吸入沙丁胺醇,可有效减少炎症细胞数量,缓解气道水肿与阻塞,缓解临床症状,缩短病程,值得推广。

Comparison of Clinical Effects of Hypertonic Solubility Saline Combined with the Salbutamol on the Treatment of the Bronchiolitis*

ABSTRACT Objective:To analyze the clinical effects of the different hypertonic saline(3.6%) combined with the salbutamol on the treatment of the bronchiolitis for children.Methods: 78 children with bronchiolitis who were treated in our hospital from January 2012 to February 2013 were selected and randomly divided into the treatment group and the control group with 39 cases in each one. Besides of the basic treatment, the patients in the control group were treated by the normal saline combined with salbutamol atomization inhalation, while the patients in the treatment group was given 3.6% hypertonic saline combined with salbutamol atomization inhalation. Then the sputum inflammatory of cells and the clinical efficacy were observed and compared. Results:The cure rate of the treatment group was 94.87%(37/39) which was higher than 82.05%(32/39) of the control group with statistically significant differences (P<0.05). After the treatment for 5 days, the total sputum inflammatory cells was lower than that of the control group (P<0.01).Conclusion: It is suggested that the combination of 3.6% hypertonic saline and nebulizer salbutamol on the treatment of the bronchiolitis for children could be well promoted to the clinical with the advantages of reducing the inflammatory cells as well as improving the clinical symptoms.