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Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process |
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| Authors: | Yin Shouliang Li Zilong Wang Xuefeng Wang Huizhuan Jia Xiaole Ai Guomin Bai Zishang Shi Mingxin Yuan Fang Liu Tiejun Wang Weishan Yang Keqian |
| Affiliation: | 1.State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, 100101, People’s Republic of China ;2.Shengxue Dacheng Pharmaceutical Co., Ltd., Shijiazhuang, 051430, Hebei, People’s Republic of China ; |
| Abstract: | Applied Microbiology and Biotechnology - Heterologous expression is an important strategy to activate biosynthetic gene clusters of secondary metabolites. Here, it is employed to activate and... |
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