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Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone
Authors:Christian Krug  Katrin Birkholz  Alexander Paulus  Michael Schwenkert  Patrick Schmidt  Nicole Hoffmann  Andreas Hombach  Georg Fey  Hinrich Abken  Gerold Schuler  Beatrice Schuler-Thurner  Jan Dörrie  Niels Schaft
Affiliation:1. Department of Dermatology, Universit?tsklinikum Erlangen, Hartmannstra?e 14, 91052, Erlangen, Germany
4. Department of Biology, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany
2. Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
3. Department I Internal Medicine, University Hospital Cologne, Cologne, Germany
Abstract:
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