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| 戈登链球菌的生物学特性及在黏膜疫苗的应用 | |
| 引用本文： | 贾 平,杜先智. 戈登链球菌的生物学特性及在黏膜疫苗的应用[J]. 微生物学报, 2008, 35(6): 0944-0948 |
| 作者姓名： | 贾 平 杜先智 |
| 作者单位： | 重庆医科大学附属第二医院 重庆 400010;重庆医科大学附属第二医院 重庆 400010 |
| 基金项目： | 国家自然科学基金专项基金项目(No. 30540051) |
| 摘 要： | 戈登氏链球菌是一种非致病性革兰氏阳性黏膜共生菌, 参与组成人类口腔正常菌群。它具有特殊的生物学特性, 非常适合作为黏膜疫苗的载体。了解戈登氏链球菌的生物学特性, 常用表达体系及该菌在黏膜疫苗的应用情况, 将为其黏膜疫苗的进一步研制提供重要参考。 |
| 关 键 词： | 戈登氏链球菌 黏膜疫苗 疫苗载体 |
The Bionomics of Streptococcus gordonii and Its Application in Mucosa Vaccine |
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| JIA Ping and DU Xian-Zhi. The Bionomics of Streptococcus gordonii and Its Application in Mucosa Vaccine[J]. Acta microbiologica Sinica, 2008, 35(6): 0944-0948 | |
| Authors: | JIA Ping and DU Xian-Zhi |
| Affiliation: | The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010;The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010 |
| Abstract: | Streptococcus gordonii is a nonpathogenic gram-positive commensal bacterium and component of the normal microbial flora of the human oral cavity. It is suitable to be as a mucosa vaccine vector due to its special bionomics. knowing the bionomics of Streptococcus gordonii , the general expressing system , and the application of it in mucosa vaccine, will provid important reference for the further development of its mucosa vaccine. |
| Keywords: | Streptococcus gordonii Mucosa vaccine Vaccine vector |
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