滋肾骨康丸治疗骨质疏松症的临床研究

目的：观察滋肾骨康丸治疗骨质疏松症的临床疗效，并对该药的作用机理进行探讨。方法：将60例病人随机分为治疗组（滋肾骨康丸组）及对照组（西药组），根据2组骨密度、骨痛、中医证候结果及临床总体疗效为指标进行比较。结果：治疗组治疗后总有效率为95．8％，对照组治疗后总有效率为75．3％，差异有统计学意义（P〈0．01）；2组治疗前后骨密度无显著性差异（P〉0．05）；治疗组治疗后骨痛有效率为92．5％。优于对照组的7313％（P〈0．05）；治疗后治疗组中医证候有效率为100％，明显优于对照组的53.3％（P〈0．01）。结论：滋肾骨康丸能显著改善骨痛、肾虚证候，总体改善临床症状，具有较好的治疗作用，值得进一步推广。

The Clinical Trial of Zishengukang Pill Treating Osteoporosis

Objective： To study the effects of Zishengukang pill in the treatment of postmenopausal osteoporosis. Methods： 60 cases of osteoporosis were divided randomly into Chinese herb group and west drug control group. The parameters such as clinical curative effect, bone mineral density（BMD）, bone ache and syndrome of Chineses medicine were observed. Results： Total effective rate of Zishengukang pill group（95.8%） were more significant than that of west drug control group （75.3%）（P〈0.01）. On the effective rate of bone ache, Zishengukang pill group（92.5%） were more significant than that of west drug control group （73.3%）（P〈0.05）. On the effect of syndrome of Chineses medicine, Zishengukang pill group （100%） were more significant than that of west drug control group（53.3%）（P〈0.01）. There was no significantly difference between Zishengukang pill group and west drug control group on the results of BMD. Conclusion： Zishengukang pill possessed better effect on treating postmenopausal osteoporosis than west durg.