|
|||||
|
|
Stimulation of cell growth in the U-937 human myeloid cell line by honey royal jelly protein |
|
| Authors: | Kazuhiko Watanabe Hiroshi Shinmoto Masuko Kobori Tojiro Tsushida Kazuki Shinohara Jun Kanaeda Masami Yonekura |
| Affiliation: | (1) School of Agriculture, Ibaraki University, 3-21-1 Ami, Ibaraki, 300-03, Japan;(2) Present address: Ito-en Co. Ltd., 21 Megami, Sagara-cho, Shizuoka, 421-05, Japan;(3) Ministry of Agriculture, Forestry and Fisheries, National Food Research Institute, 2-1-2 Kannondai, Tsukuba, Ibaraki, 305, Japan;(4) Present address: Fisheries Agency, National Research Institute of Fisheries Science, 2-12-4 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236, Japan;(5) API Co. Ltd., Research Institute, 4-23 Shinhon-machi, Kanoh, Gifu, 500, Japan;(6) School of Agriculture, Ibaraki University, 3-21-1 Ami, Ibaraki, 300-03, Japan |
| Abstract: | Royal jelly was fractionated by ion-exchange chromatography and a protein (DIII protein) that had growth stimulating activity to the U-937 human myeloid cell line was obtained. The molecular weight of the DIII protein was 58 kDa on SDS-PAGE. The growth stimulating activity of the DIII protein was shown to be relatively heat and pH stable. |
| Keywords: | cell differentiation growth factor royal jelly U-937 |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |