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Quantification by fluorescence of apurinic sites in DNA |
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| Authors: | J R Bertrand C Malvy C Paoletti |
| Abstract: | Time dependent fluorescence is observed when single or double stranded DNA with apurinic sites are mixed with 9-NH2-ellipticine. A concentration dependent plateau is obtained which is linearly related to the ratio of apurinic sites in DNA. We therefore suggest that it is possible to have a direct measurement of apurinic sites in DNA by fluorescence. |
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