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冠心病患者血清白介素-6和C-反应蛋白的水平变化及临床意义
引用本文:朱晓芳,孔玮,李芳. 冠心病患者血清白介素-6和C-反应蛋白的水平变化及临床意义[J]. 微生物学免疫学进展, 2006, 34(4): 58-60
作者姓名:朱晓芳  孔玮  李芳
作者单位:1. 广州市荔湾区中医院检验科,广州,510140
2. 广东省珠江医院检验科,广州,510282
3. 广东省人民医院检验科,广州,510080
摘    要:探讨白介素-6(IL-6)和C-反应蛋白(CRP)在冠心病(CHD)的发生发展中所起的作用及其之间的相互关系和临床意义。对70例住院冠心病患者采用ELISA和散射比浊法分别测定其血清中的IL-6、CRP水平的变化并与同期体检健康者34例作对照。显示患者CRP、IL-6值均明显高于对照组,差异显著(P<0.01)。炎症反应在冠心病的发生发展中起着重要的作用。如果能够在测定病人CRP及IL-6水平的同时建立患者的个体标准,则可以对患者病变程度及预后提供更好的临床依据。

关 键 词:冠心病  C-反应蛋白  IL-6
文章编号:1005-5673(2006)04-0058-03
收稿时间:2006-03-01
修稿时间:2006-06-24

Serum levels of IL-6 and CRP in coronary heart disease
ZHU Xiao-fang,KONG Wei,LI Fang. Serum levels of IL-6 and CRP in coronary heart disease[J]. Progress In Microbiology and Immunology, 2006, 34(4): 58-60
Authors:ZHU Xiao-fang  KONG Wei  LI Fang
Abstract:To elucidate the effects of interleukin-6(IL-6) and C-reactive protein(CRP) in coronary heart disease(CHD),seventy patients suffered from CHD in a test group and 34 health persons as a control group were involved in this study.Serum levels of IL-6 and CRP were measured by ELISA and nephelometery.The concentrations of IL-6 and CRP in CHD test group were significantly higher than those in control group,which showed some clinical importance.The increment of serum levels of IL-6 and CRP are indicators for the development of CHD.
Keywords:Coronary heart disease CHD)  C-reactive protein(CRP)  Interleukin-6(IL-6)
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