Membrane Proteins: The Key Players of a Cancer Cell |
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Authors: | Email author" target="_blank">Kim?R?KampenEmail author |
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Institution: | (1) Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands |
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Abstract: | Membrane proteins are involved in the prognosis of the most common forms of cancer. Membrane proteins are the hallmark of
a cancer cell. The overexpressed membrane receptors are becoming increasingly important in cancer cell therapy. Current renewing
therapy approaches based on receptor overexpression include; antibody therapy, nanocarrier drug delivery, and fluorescent
tumor imaging in surgery. Gene profiling reveals cancer specific signatures and may identify membrane proteins that are related
to cancer progression and lead to the development of improved therapy strategies in the future. |
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Keywords: | |
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