Dietary boron does not affect tooth strength,micro-hardness,and density,but affects tooth mineral composition and alveolar bone mineral density in rabbits fed a high-energy diet |
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| Institution: | 1. Selcuk University, Faculty of Dentistry, Department of Periodontology, Konya 42079, Turkey;2. Inonu University, Faculty of Dentistry, Department of Orthodontics, Malatya, Turkey;3. Selcuk University, Research Center of Faculty of Dentistry, Konya, Turkey;4. Selcuk University, Faculty of Agriculture, Department of Animal Science, Konya, Turkey;5. Selcuk University, Faculty of Agriculture, Department of Soil Science and Plant Nutrition, Konya, Turkey;6. Selcuk University, Faculty of Veterinary Medicine Department of Biochemistry, Konya, Turkey;7. Selcuk University, Faculty of Veterinary Medicine, Department of Internal Medicine, Konya, Turkey;8. USDA, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58202, USA;9. Bonn University, Medical Faculty, Department of Orthodontics, Oral Biology Lab, Bonn, Germany;1. Department of Pharmacy Practice, University of Toledo, Toledo, OH;2. University of Mississippi, Oxford, MS;3. Jobst Vascular Institute of ProMedica Hospitals, Toledo, OH;4. Jobst Vascular Institute of ProMedica and Division of Vascular Surgery, University of Michigan, Ann Arbor, MI;1. Division of Biomaterials and Bioengineering, Department of Preventive and Restorative Dental Sciences, School of Dentistry, University of California, San Francisco, San Francisco, CA 94143, United States;2. Materials Division, The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, United States;1. College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, PR China;2. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, PR China;3. Bijie Pilot Area Research Institute, Bijie University, Bijie 551700, PR China;1. School of Kinesiology and Health Studies, Division of Endocrinology and Metabolism, Queen''s University, Kingston, ON, K7L 3N6 Canada;2. Department of Medicine, Division of Endocrinology and Metabolism, Queen''s University, Kingston, ON, K7L 3N6 Canada;1. Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA;2. Children’s Hospital Oakland Research Institute, Oakland, CA 94609, USA;3. University of Colorado, School of Medicine, Aurora, CO 80045, USA;4. Departments of Surgery and Cell and Molecular Physiology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA |
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| Abstract: | The objective of this study was to determine whether dietary boron (B) affects the strength, density and mineral composition of teeth and mineral density of alveolar bone in rabbits with apparent obesity induced by a high-energy diet. Sixty female, 8-month-old, New Zealand rabbits were randomly assigned for 7 months into five groups as follows: (1) control 1, fed alfalfa hay only (5.91 MJ/kg and 57.5 mg B/kg); (2) control 2, high energy diet (11.76 MJ and 3.88 mg B/kg); (3) B10, high energy diet + 10 mg B gavage/kg body weight/96 h; (4) B30, high energy diet + 30 mg B gavage/kg body weight/96 h; (5) B50, high energy diet + 50 mg B gavage/kg body weight/96 h. Maxillary incisor teeth of the rabbits were evaluated for compression strength, mineral composition, and micro-hardness. Enamel, dentin, cementum and pulp tissue were examined histologically. Mineral densities of the incisor teeth and surrounding alveolar bone were determined by using micro-CT. When compared to controls, the different boron treatments did not significantly affect compression strength, and micro-hardness of the teeth, although the B content of teeth increased in a dose-dependent manner. Compared to control 1, B50 teeth had decreased phosphorus (P) concentrations. Histological examination revealed that teeth structure (shape and thickness of the enamel, dentin, cementum and pulp) was similar in the B-treated and control rabbits. Micro CT evaluation revealed greater alveolar bone mineral density in B10 and B30 groups than in controls. Alveolar bone density of the B50 group was not different than the controls. Although the B treatments did not affect teeth structure, strength, mineral density and micro-hardness, increasing B intake altered the mineral composition of teeth, and, in moderate amounts, had beneficial effects on surrounding alveolar bone. |
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| Keywords: | Boron Teeth Alveolar bone Teeth composition Minerals |
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