Two single nucleotide polymorphisms in the human nescient helix-loop-helix 2 (NHLH2) gene reduce mRNA stability and DNA binding |
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Authors: | Numan AL_Rayyan Umesh D. WankhadeKorie Bush Deborah J. Good |
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Affiliation: | Department of Human Nutrition, Foods and Exercise, Virginia Tech University, Blacksburg, VA 24061, USA |
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Abstract: |
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Keywords: | A, adenosine ARE, AU-rich element βgal, beta galactosidase bHLH, basic helix-loop-helix bp, base pair C, cytosine dATP, deoxy adenosine tri-phosphate DNA, deoxyribonucleic acid G, guanosine kb, kilobase KO, knockout MC4R, melanocortin 4 receptor μg, microgram μl, microliter mRNA, messenger ribonucleic acid miRNA, micro ribonucleic acid NCBI, National Center for Biotechnology Information ng, nanogram NHLH2, nescient helix-loop-helix 2 (human) Nhlh2, nescient helix-loop-helix 2 (mouse) nt, nucleotide oligo, oligonucleotide PC1/3, prohormone convertase 1/3 QPCR, quantitative polymerase chain reaction rRNA, ribosomal ribonucleic acid SDS, sodium dodecyl sulfate SNP, single nucleotide polymorphism SV-40, simian virus 40 T, thymidine U, uridine UTR, untranslated region V, volts WT, wild type |
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