Antibacterial activity of flavanostilbenes against methicillin-resistant Staphylococcus aureus |
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| Authors: | M Sato H Tsuchiya T Miyazaki M Ohyama T Tanaka M Iinuma |
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| Institution: | Departments of Oral Microbiology, Asahi University School of Dentistry, Gifu;Dental Pharmacology, Asahi University School of Dentistry, Gifu;Department of Pharmacognosy, Gifu Pharmaceutical University, Gifu, Japan |
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| Abstract: | Three phytochemical compounds (alopecurone A-C), flavanostilbenes which are produced by condensation between a hydroxyflavanone and a hydroxystilbene, were isolated as major components from the root of Sophora alopecuroides . They uniformly inhibited the growth of 21 strains of methicillin-resistant Staphylococcus aureus with minimum inhibitory concentrations of 3·13–6·25 μg ml-1. |
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