Department of Genetics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, ul. Rakowiecka 36, 02-532 Warszawa Poland
Abstract:
Nitrous acid (NA) induced mutations efficiently in mitDNA, conferring resistance to erythromycin and weakly induces mit- mutations. In some strains of yeast it also enhanced rho- mutations. The frequencies of nuclear and mitochondrial mutations induced with NA are compared.