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Association of three polymorphisms in ARID5B, IKZF1and CEBPE with the risk of childhood acute lymphoblastic leukemia in a Chinese population
Authors:Yaping Wang  Jing Chen  Jie Li  Jianping Deng  Yaoyao Rui  Qin Lu  Meilin Wang  Na Tong  Zhengdong Zhang  Yongjun Fang
Affiliation:1. Department of Hematology and Oncology, Nanjing Children''s Hospital Affiliated to Nanjing Medical University, Nanjing 210008, China;2. Department of Hematology and Oncology, Shanghai Children''s Medical Center Affiliated to Shanghai Jiao Tong University, Shanghai 200127, China;3. Department of Hematology and Oncology, Soochow Children''s Hospital Affiliated to Soochow University, Suzhou 215001, China;4. Department of Molecular and Genetic Toxicology, Cancer Center of Nanjing Medical University, Nanjing 210029, China
Abstract:
Keywords:ALL, acute lymphoblastic leukemia   GWAS, genome-wide association studies   ARID5B, AT rich interactive domain 5B   IKZF1, Ikaros zinc finger 1   CEBPE, CCAAT/enhancer-binding protein ε   OR, odds ratio   CI, confidence interval   SAS, Statistical Analysis System   CEBPs, CCAAT/enhancer-binding proteins   IGH, immunoglobulin heavy-chain   BCP-ALL, B-cell precursor acute lymphoblastic leukemia   3&prime  UTR, 3&prime   untranslated region   MRD, minimal residual disease
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