Influenza A: From highly pathogenic H5N1 to pandemic 2009 H1N1. Epidemiology and clinical features |
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Authors: | Randeep Guleria Jaya Kumar Anant Mohan Naveet Wig |
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Institution: | 1.Department of Medicine,All India Institute of Medical Sciences,New Delhi,India |
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Abstract: | The last decade has seen the emergence of two new influenza A subtypes and they have become a cause of concern for the global
community. These are the highly pathogenic H5N1 influenza A virus (H5N1) and the Pandemic 2009 influenza H1N1 virus. Since
2003 the H5N1 virus has caused widespread disease and death in poultry, mainly in south East Asia and Africa. In humans the
number of cases infected with this virus is few but the mortality has been about 60%. Most patients have presented with severe
pneumonia and acute respiratory distress syndrome. The second influenza virus, the pandemic H1N1 2009, emerged in Mexico in
March this year. This virus acquired the ability for sustained human to human spread and within a few months spread throughout
the world and infected over 4 lakh individuals. The symptoms of infection with this virus are similar to seasonal influenza
but it currently affecting younger individuals more often. Fortunately the mortality has been low. Both these new influenza
viruses are currently circulating and have different clinical and epidemiological characteristics. |
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Keywords: | Influenza A Pandemic H1N1 |
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