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Inductive formation of celluases by L-sorbose in Trichoderma reesei
Authors:Mikio Kawamori  Yasushi Morikawa  Seigo Takasawa
Institution:(1) Tokyo research Laboratories, Kyowa Hakko Kogyo Co. Ltd., Asahimachi, 194 Machida-shi, Tokyo, Japan;(2) Research and Development Division, Kyowa Hakko Kogyo Co. Ltd, Otemachi, Chiyoda-ku, 100 Tokyo, Japan
Abstract:Summary L-Sorbose, which is known as an inhibitor of beta-1,3-glucan synthesis in fungi, induces the production of cellulases in strains belonging to Trichoderma reesei. Especially, mutant strains PC-3–7 and X-31, which were obtained by several steps of mutation from QM 9414, have the most effective cellulase inducibility by L-sorbose comparing with other mutants of Trichoderma reesei. They synthesized cellulases effectively in liquid culture, whenever the alkaline treated sugarcane bagasse was used as a main carbon source for lowering the cost of cellulase production.
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