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[3-Azabicyclo[3.1.0]hex-1-yl]phenyl-benzenesulfonamides as selective dopamine D3 antagonists
Authors:Fabrizio Micheli  Dieter Hamprecht  Giorgio Bonanomi  Romano Di Fabio  Daniele Donati  Gabriella Gentile  Christian Heidbreder  Adolfo Prandi  Luca Tarsi  Silvia Terreni
Affiliation:1. Neurosciences Centre of Excellence, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy;2. Boehringer Ingelheim, Milan, Italy;3. Nerviano Medical Science, Milan, Italy;4. Reckitt Benckiser Pharmaceuticals, Richmond, USA;5. Centro Interdisciplinare di Studi bio-molecolari e applicazioni Industriali (CISI), Milan, Italy
Abstract:A new class of azabicyclo[3.1.0]benzenesulfonamides is presented as selective dopamine D3 antagonists together with SAR and selectivity data.
Keywords:
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