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Reactive oxygen species play a role in P2X7 receptor-mediated IL-6 production in spinal astrocytes |
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| Authors: | Munoz Frances M Patel Priya A Gao Xinghua Mei Yixiao Xia Jingsheng Gilels Sofia Hu Huijuan |
| Institution: | 1.Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA, USA ;2.Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China ;3.Department of Anesthesiology, Rutgers New Jersey Medical School, 185 S. Orange Ave., Newark, NJ, 07103, USA ; |
| Abstract: | Purinergic Signalling - Astrocytes mediate a remarkable variety of cellular functions, including gliotransmitter release. Under pathological conditions, high concentrations of the purinergic... |
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