Synthesis,antibacterial and antifungal activities of some carbazole derivatives |
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| Authors: | Fei-Fei Zhang Lin-Ling Gan Cheng-He Zhou |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China;2. School of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China |
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| Abstract: | A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains. |
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