Interaction of cyanine dyes with nucleic acids. XII.beta-substituted carbocyanines as possible fluorescent probes for nucleic acids detection. |
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Authors: | S M Yarmoluk V B Kovalska S S Lukashov Y L Slominskii |
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Affiliation: | Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv. |
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Abstract: | Results of investigations of fluorescent properties of a beta-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented. Carbocyanine substituted in polymethine chain has shown promising properties for use as a fluorescent probe in homogeneous systems of nucleic acids detection. |
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