慢性盆腔炎患者支原体、衣原体感染状况分析

目的了解慢性盆腔炎患者支原体与沙眼衣原体的感染状况并对支原体的药敏试验结果进行分析,为临床防治提供依据。方法选取2011年1月至2013年12月来院就诊的慢性盆腔炎患者680例,无菌采集宫颈分泌物,培养法检测解脲支原体和人型支原体,用免疫层析法检测沙眼衣原体。结果共检出解脲支原体（Uu）290例（42.6%）,人型支原体（Mh）53例（7.8%）,两者混合感染（Uu＋Mh）76例（11.2%）,沙眼衣原体（Ct）感染58例（8.5%）。Uu感染在20~40岁年龄段阳性率最高（P〈0.05）,Mh、Uu＋Mh和Ct在各年龄段阳性率差异无统计学意义（P〉0.05）。药物敏感染性结果显示,支原体对交沙霉素、强力霉素和美满霉素的耐药率较低,对环丙沙星、左氧氟沙星和加替沙星的耐药率较高。结论解脲支原体和沙眼衣原体为慢性盆腔炎的重要致病因素,临床应重视宫颈解脲支原体和沙眼衣原体的检测。防治解脲支原体和沙眼衣原体感染,可能有益于预防慢性盆腔炎的发生。

Infection of Mycoplasma and Chlamydia trachomatis in patients with chronic pelvic inflammation disease

Objective To explore the Mycoplasma and Chlamydia trachomatis infection status among patients with chronic pelvic inflammation disease and analyze antimicrobial susceptibility of mycoplasma,and provide basis for clinical prevention and treatment. Methods 680 patients with chronic pelvic inflammation disease from Jan. 2011 to Dec. 2013 were selected; the cervical secretion specimens were collected. The Ureaplasma mycoplasma（ Uu）and Human mycoplasma（ Mh） were detected by culture and Chlamydia trachomatis（ Ct） was detected by immune chromatography. Results A total of 290 cases（ 42. 6%） of Uu,53 cases（ 7. 8%） of Mh,76 cases（ 11. 2%） of Uu ＋ Mh and 58 cases（ 8. 5%） of Ct were detected. Uu infection rate was the highest in 20 to 40 ages（ P〈 0. 05）. Mh,Uu ＋ Mh and Ct had no significant differences among all ages（ P〉 0. 05）. The drug resistance of Mycoplasma was lower to Josamycin,Doxycycline and Azithromycin,while higher to Ciprofloxacin,Levofloxacin and Gatifloxacin. Conclusion Uu and Ct are the important pathogenic factors that cause chronic pelvic inflammation disease. Uu and Ct detection are important for clinical treatment. Prevention of Uu and Ct infections may help prevent the ocurrence of chronic pelvic inflammation disease.