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幽门螺杆菌相关性胃炎的细胞免疫功能的研究
引用本文:郭公新,王兴权,卓越,颜玉,杨景云.幽门螺杆菌相关性胃炎的细胞免疫功能的研究[J].中国微生态学杂志,2004,16(2):96-96,99.
作者姓名:郭公新  王兴权  卓越  颜玉  杨景云
作者单位:1. 佳木斯大学第一附属医院,消化科,黑龙江,佳木斯,154002
2. 佳木斯永红医院
3. 佳木斯大学基础医学院
摘    要:目的:探讨细胞免疫在Helicobacter pylori(Hp)相关性胃炎的损伤中的作用.方法:检测外周血T淋巴细胞亚群及IL-2、sIL-2R、IL-6、IL-8水平.结果:病例组与对照组比较,CD3 、CD 4和CD 4/CD 8比值及血清IL-2水平均显著降低(P<0.01),而sIL-2R、IL-6和IL-8水平均显著升高(P<0.01).结论:细胞免疫在Hp相关性胃炎的损伤中作用明显,检测细胞免疫功能对Hp相关性胃炎的病情监测、疗效观察及预后判定有一定价值.

关 键 词:螺杆菌  幽门  胃炎  细胞免疫
文章编号:1005-376X(2004)02-0096-02

Study on tbe cell immunity function of Helicobacter pylori-associated gastritis
GUO Gong-xin,WANG Xing-quan,ZHUO Yue,et al..Study on tbe cell immunity function of Helicobacter pylori-associated gastritis[J].Chinese Journal of Microecology,2004,16(2):96-96,99.
Authors:GUO Gong-xin  WANG Xing-quan  ZHUO Yue  
Abstract:Objective:To study the effect of cell immunity function on Hp-associated gastritis.Methods:45 pationts with Hp-associated gastritis were detected for the levels of the second cluster of T lymph cell and IL-2,sIL-2,IL-6,IL-8 in venous plasma.Results:The levels of CD 3,CD 4 and CD 4/CD 8 were significantly lower than that of control group(P<0.01).But the levels of sIL-2R,IL-6 and IL-8 were significantly higher than that of control group(P<0.01).Conclusion:The cell immunity fuction plays an important role in injury of Hp-associated gastritis.
Keywords:Helicobacter pylori  Gastritis  Cell immunity
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